shame: 1. an unlucky situation: ~~~It's a shame that the concert had to be cancelled. ~~~"Douglas is having to miss the school concert because he's ill." "Oh, what a shame!"
2. a bad feeling of guilt
shame on you: used to tell someone that they should feel sorry for something they did(can be friendly): ~~~Shame on you for being so unkind. ~~~HUMOROUS You mean you were in town and you didn't come and see us - shame on you!