很多内容大家都知道了

但也有些新料，值得花时间一读…

The Lab-Leak Theory: Inside the Fight to Uncover COVID-19’s Origins

Throughout 2020, the notion that the novel coronavirus leaked from a lab was off-limits. Those who dared to push for transparency say toxic politics and hidden agendas kept us in the dark.

https://www.vanityfair.com/news/2021/06/the-lab-leak-theory-inside-the-fight-to-uncover-covid-19s-origins

2019年9月，病毒数据库下线的时间，和武汉同期应对新冠病毒感染者的演练，纯属巧合？

They paid one visit to the Wuhan Institute of Virology, where they met with Shi Zhengli, as recounted in an annex to the mission report. One obvious demand would have been access to the WIV’s database of some 22,000 virus samples and sequences, which had been taken offline. At an event convened by a London organization on March 10, Daszak was asked whether the group had made such a request. He said there was no need: Shi Zhengli had stated that the WIV took down the database due to hacking attempts during the pandemic. “Absolutely reasonable,” Daszak said. “And we did not ask to see the data…. As you know, a lot of this work has been conducted with EcoHealth Alliance…. We do basically know what’s in those databases. There is no evidence of viruses closer to SARS-CoV-2 than RaTG13 in those databases, simple as that.”

In fact, the database had been taken offline on September 12, 2019, three months before the official start of the pandemic, a detail uncovered by Gilles Demaneuf and two of his DRASTIC colleagues.

June 6, 2021 更新

我把最近一个月以来围绕新冠病毒溯源的主要事件按时间线总结了一下，欢迎大家评论补充

May 5: Former New York Times science reporter Nicholas Wade, writing in the Bulletin of the Atomic Scientists, reviews the evidence and makes a strong case for the lab-leak theory. He focuses in particular on the furin cleavage site, which increases viral infectivity for human cells. His analysis yields this quote from David Baltimore, a virologist and former president of the California Institute of Technology: “When I first saw the furin cleavage site in the viral sequence, with its arginine codons, I said to my wife it was the smoking gun for the origin of the virus. These features make a powerful challenge to the idea of a natural origin for SARS2.”

https://thebulletin.org/2021/05/the-origin-of-covid-did-people-or-nature-open-pandoras-box-at-wuhan/

May 7: James Freeman, Assistant editor, editorial page, The Wall Street Journal became the first reporter of a major news outlet challenging the intertwined relationship among China, Fauci and Origins of COVID

https://www.wsj.com/articles/china-fauci-and-the-origins-of-covid-11620419989

May 11: During a Senate hearing on the pandemic response, Paul alleged that the National Institutes of Health (NIH) had been sending funding to the Wuhan lab, which then "juiced up" a virus that was originally found in bats to create a super virus that can infect human cells. Paul pressed Fauci on the theory that the novel coronavirus was created in the Wuhan lab, and then somehow escaped, either because of an accident or because it was deliberately released.

https://thehill.com/policy/healthcare/552857-rand-paul-clashes-with-fauci-over-coronavirus-origins

May 14: Eighteen prominent scientists publish a letter in the journal Science, saying a new investigation is needed because “theories of accidental release from a lab and zoonotic spillover both remain viable.” One signer is Ralph Baric, a virologist who worked closely with Shi.

https://science.sciencemag.org/content/372/6543/694.1

May 17: Another former New York Times science reporter, Donald G. McNeil Jr., posts on Medium: “How I Learned to Stop Worrying And Love the Lab-Leak Theory.” He quotes W. Ian Lipkin of Columbia University — who had signed the March 2020 letter in Nature Medicine — as saying his mind had changed in light of new information.

https://donaldgmcneiljr1954.medium.com/how-i-learned-to-stop-worrying-and-love-the-lab-leak-theory-f4f88446b04d

May 23: WSJ published an exclusive news piece which reports three researchers from China’s Wuhan Institute of Virology became sick enough in November 2019 that they sought hospital care, according to a previously undisclosed U.S. intelligence report that could add weight to growing calls for a fuller probe of whether the Covid-19 virus may have escaped from the laboratory.

https://www.wsj.com/articles/intelligence-on-sick-staff-at-wuhan-lab-fuels-debate-on-covid-19-origin-11621796228

May 24: Anthony Fauci, apparently “changed” his mind, admitted earlier this month that he is no longer convinced that the Covid-19 pandemic originated naturally.

Same day, Dr. Scott Gottlieb, the 23rd commissioner of the Food and Drug Administration (FDA), said the growing number of reports provide an increasing amount of circumstantial evidence supporting the theory that the virus could have escaped from a lab.

https://www.cnn.com/2021/05/24/politics/fauci-donald-trump-coronavirus/index.html

https://www.cnbc.com/2021/05/24/gottlieb-says-theres-growing-circumstantial-evidence-that-covid-may-have-originated-in-a-lab.html

May 26: President Biden ordered the Intelligence Community to redouble their efforts to collect and analyze information that could bring us closer to a definitive conclusion, and to report back in 90 days.

Same day, The Editorial Board of WSJ endorsed the credibility of The Virus Lab Theory

https://www.whitehouse.gov/briefing-room/statements-releases/2021/05/26/statement-by-president-joe-biden-on-the-investigation-into-the-origins-of-covid-19/

https://www.wsj.com/articles/the-virus-lab-theorys-new-credibility-11622066808

June 2: Uncovered Emails Show Fauci’s deep involvement in Gain of Function research

https://assets.documentcloud.org/documents/20793561/leopold-nih-foia-anthony-fauci-emails.pdf

June 3: Vanity Fair published a nearly 12,000-word article by award-winning journalist Katherine Eban; it''''''''''''''''''''''''''''''''s much worth reading on the bottom line question of whether COVID-19 indeed stemmed from a lab leak.

https://www.vanityfair.com/news/2021/06/the-lab-leak-theory-inside-the-fight-to-uncover-covid-19s-origins

June 6:

https://www.cbsnews.com/news/covid-19-wuhan-origins-60-minutes-2021-06-06/#app

https://www.wsj.com/articles/the-science-suggests-a-wuhan-lab-leak-11622995184

这是言论自由和新闻自由对公民社会和事实真相无比重要的佐证！

A months long Vanity Fair investigation, interviews with more than 40 people, and a review of hundreds of pages of U.S. government documents, including internal memos, meeting minutes, and email correspondence, found that conflicts of interest, stemming in part from large government grants supporting controversial virology research, hampered the U.S. investigation into COVID-19’s origin at every step. 

谢谢分享中文摘要

我总结了一下名利场这篇文章跟研究有关的几点。

何小满 发表于 2021-06-05 22:59

辛苦了！摘要总结得很不错，信达雅！赞👍

我把最近一个月以来围绕新冠病毒溯源的主要事件按时间线总结了一下，欢迎大家评论补充

May 5: Former New York Times science reporter Nicholas Wade, writing in the Bulletin of the Atomic Scientists, reviews the evidence and makes a strong case for the lab-leak theory. He focuses in particular on the furin cleavage site, which increases viral infectivity for human cells. His analysis yields this quote from David Baltimore, a virologist and former president of the California Institute of Technology: “When I first saw the furin cleavage site in the viral sequence, with its arginine codons, I said to my wife it was the smoking gun for the origin of the virus. These features make a powerful challenge to the idea of a natural origin for SARS2.”

https://thebulletin.org/2021/05/the-origin-of-covid-did-people-or-nature-open-pandoras-box-at-wuhan/

May 7: James Freeman, Assistant editor, editorial page, The Wall Street Journal became the first reporter of a major news outlet challenging the intertwined relationship among China, Fauci and Origins of COVID

https://www.wsj.com/articles/china-fauci-and-the-origins-of-covid-11620419989

May 11: During a Senate hearing on the pandemic response, Paul alleged that the National Institutes of Health (NIH) had been sending funding to the Wuhan lab, which then "juiced up" a virus that was originally found in bats to create a super virus that can infect human cells. Paul pressed Fauci on the theory that the novel coronavirus was created in the Wuhan lab, and then somehow escaped, either because of an accident or because it was deliberately released.

https://thehill.com/policy/healthcare/552857-rand-paul-clashes-with-fauci-over-coronavirus-origins

May 14: Eighteen prominent scientists publish a letter in the journal Science, saying a new investigation is needed because “theories of accidental release from a lab and zoonotic spillover both remain viable.” One signer is Ralph Baric, a virologist who worked closely with Shi.

https://science.sciencemag.org/content/372/6543/694.1

May 17: Another former New York Times science reporter, Donald G. McNeil Jr., posts on Medium: “How I Learned to Stop Worrying And Love the Lab-Leak Theory.” He quotes W. Ian Lipkin of Columbia University — who had signed the March 2020 letter in Nature Medicine — as saying his mind had changed in light of new information.

https://donaldgmcneiljr1954.medium.com/how-i-learned-to-stop-worrying-and-love-the-lab-leak-theory-f4f88446b04d

May 23: WSJ published an exclusive news piece which reports three researchers from China’s Wuhan Institute of Virology became sick enough in November 2019 that they sought hospital care, according to a previously undisclosed U.S. intelligence report that could add weight to growing calls for a fuller probe of whether the Covid-19 virus may have escaped from the laboratory.

https://www.wsj.com/articles/intelligence-on-sick-staff-at-wuhan-lab-fuels-debate-on-covid-19-origin-11621796228

May 24: Anthony Fauci, apparently “changed” his mind, admitted earlier this month that he is no longer convinced that the Covid-19 pandemic originated naturally.

Same day, Dr. Scott Gottlieb, the 23rd commissioner of the Food and Drug Administration (FDA), said the growing number of reports provide an increasing amount of circumstantial evidence supporting the theory that the virus could have escaped from a lab.

https://www.cnn.com/2021/05/24/politics/fauci-donald-trump-coronavirus/index.html

https://www.cnbc.com/2021/05/24/gottlieb-says-theres-growing-circumstantial-evidence-that-covid-may-have-originated-in-a-lab.html

May 26: President Biden ordered the Intelligence Community to redouble their efforts to collect and analyze information that could bring us closer to a definitive conclusion, and to report back in 90 days.

Same day, The Editorial Board of WSJ endorsed the credibility of The Virus Lab Theory

https://www.whitehouse.gov/briefing-room/statements-releases/2021/05/26/statement-by-president-joe-biden-on-the-investigation-into-the-origins-of-covid-19/

https://www.wsj.com/articles/the-virus-lab-theorys-new-credibility-11622066808

June 2: Uncovered Emails Show Fauci’s deep involvement in Gain of Function research

https://assets.documentcloud.org/documents/20793561/leopold-nih-foia-anthony-fauci-emails.pdf

June 3: Vanity Fair published a nearly 12,000-word article by award-winning journalist Katherine Eban; it's much worth reading on the bottom line question of whether COVID-19 indeed stemmed from a lab leak.

https://www.vanityfair.com/news/2021/06/the-lab-leak-theory-inside-the-fight-to-uncover-covid-19s-origins

也许（非常大概率）溯源的结果就是没有“定论” (Dr. Gottlieb评论） - 你懂的...

但是，公道自在人心

人在做，天在看

远离邪恶，敬畏自然

"Under scrutiny from governments including her own, with bizarre conspiracy theories and legitimate doubts swirling around her, she began lashing out at critics. “The 2019 novel coronavirus is a punishment from nature for humanity’s uncivilized habits,” she wrote in a February 2 post on WeChat, a popular social media app in China. “I, Shi Zhengli, guarantee on my life that it has nothing to do with our lab. May I offer some advice to those people who believe and spread bad media rumors: shut your dirty mouths.”"

石正丽以生命担保新冠病毒跟她的实验室没有关系，但是武毒所还有很多其他的实验室，所以这个声明并没有为武毒所撇清干系。

fopen 发表于 2021-06-06 03:25

举个例子， “淘汰的实验受体猪、牛和牛奶”流入市场

[url]https://xw.qq.com/cmsid/20200208A0QEZ500[/url]

自2008年7月至2012年2月，相关课题在研究过程中利用科研经费购买了实验所需的猪、牛，对出售课题研究过程中淘汰的实验受体猪、牛和牛奶所得款项

没用，啥好感态度的，都是瞎扯，没人会和钱过不去。资本家只认钱。

就好比去大街上拉一个人，都说环保好，超市里一个环保的5块钱，不环保的1块钱，照样5块钱的滞销。

purpledee 发表于 2021-06-06 13:24

You can fool all the people some of the time and some of the people all the time, but you cannot fool all the people all the time.

在根本价值观生死存亡的关头，利益，真的不是决定因素。

你低估了自文艺复兴，思想启蒙后西方文明的力量！

确实是正统杂志，胸大无脑淑女的正统严肃杂志。

出现在美发美甲店椅子上，永远不会出现在大学政治专业图书馆书架上。

探听名人隐私，狗仔队，Paparazzi。政治报道也是走狗仔路数，充满脑补，耸人听闻，戏剧化情结。

数次因为编造耸人听闻故事而被告到法院。

比如波兰斯基一案，名利场说波兰斯基在Elaine餐馆搞幼女，但是事实是，波兰斯基一个月后才第一次去那家餐馆。法院判名利场撒谎诽谤。

用这种狗仔队文化来写科学溯源，结果可想而知，猜测，编造，耸人听闻，猎奇。。。充满娱乐精神，独独没有科学精神和专业素养。一个关心精液胜过关心DNA杂志，写科学溯源，可想最后写成什么。

fitzroy 发表于 2021-06-06 06:30

王顾左右而言他

有些人，对问题本身从不正面回应

相反，他们要么诋毁提出问题的人，

要么对提出问题的渠道打压封堵

解决不了问题，还解决不了有问题的人？！

求求你们，来点创意和新意好不好！

仔细读了全文，不觉得有任何证据指向实验室问题。就像现在还有人否认六十年代美国登月一样。

damulvv 发表于 2021-06-06 11:50

大家各入法眼，公道自在人心

别停留在时薪就是一切的原始概念上了。

产业链的优势，了解一下。

全世界找不到任何一个国家，你要什么就可以生产什么。缺什么都可以在方圆200mile的地方运过来。如果一个供应商提价，相似的供应商有10几个，轻轻松松换一个。

也找不到任何一个国家，可以保持稳定的政局，不至于4年后政策一变，投资血本无归。

purpledee 发表于 2021-06-06 13:42

仿佛这个世界离开了中国大陆就会停转了一样

图样图森破

The Science Suggests a Wuhan Lab Leak

The Covid-19 pathogen has a genetic footprint that has never been observed in a natural coronavirus.

By Steven Quay and Richard Muller

June 6, 2021 11:59 am ET

ILLUSTRATION: MARTIN KOZLOWSKI

The possibility that the pandemic began with an escape from the Wuhan Institute of Virology is attracting fresh attention. President Biden has asked the national intelligence community to redouble efforts to investigate. 

Much of the public discussion has focused on circumstantial evidence: mysterious illnesses in late 2019; the lab’s work intentionally supercharging viruses to increase lethality (known as “gain of function” research). The Chinese Communist Party has been reluctant to release relevant information. Reports based on U.S. intelligence have suggested the lab collaborated on projects with the Chinese military.

But the most compelling reason to favor the lab leak hypothesis is firmly based in science. In particular, consider the genetic fingerprint of CoV-2, the novel coronavirus responsible for the disease Covid-19. 

In gain-of-function research, a microbiologist can increase the lethality of a coronavirus enormously by splicing a special sequence into its genome at a prime location. Doing this leaves no trace of manipulation. But it alters the virus spike protein, rendering it easier for the virus to inject genetic material into the victim cell. Since 1992 there have been at least 11 separate experiments adding a special sequence to the same location. The end result has always been supercharged viruses. 

A genome is a blueprint for the factory of a cell to make proteins. The language is made up of three-letter “words,” 64 in total, that represent the 20 different amino acids. For example, there are six different words for the amino acid arginine, the one that is often used in supercharging viruses. Every cell has a different preference for which word it likes to use most.

In the case of the gain-of-function supercharge, other sequences could have been spliced into this same site. Instead of a CGG-CGG (known as “double CGG”) that tells the protein factory to make two arginine amino acids in a row, you’ll obtain equal lethality by splicing any one of 35 of the other two-word combinations for double arginine. If the insertion takes place naturally, say through recombination, then one of those 35 other sequences is far more likely to appear; CGG is rarely used in the class of coronaviruses that can recombine with CoV-2.

In fact, in the entire class of coronaviruses that includes CoV-2, the CGG-CGG combination has never been found naturally. That means the common method of viruses picking up new skills, called recombination, cannot operate here. A virus simply cannot pick up a sequence from another virus if that sequence isn’t present in any other virus.

Although the double CGG is suppressed naturally, the opposite is true in laboratory work. The insertion sequence of choice is the double CGG. That’s because it is readily available and convenient, and scientists have a great deal of experience inserting it. An additional advantage of the double CGG sequence compared with the other 35 possible choices: It creates a useful beacon that permits the scientists to track the insertion in the laboratory.

Now the damning fact. It was this exact sequence that appears in CoV-2. Proponents of zoonotic origin must explain why the novel coronavirus, when it mutated or recombined, happened to pick its least favorite combination, the double CGG. Why did it replicate the choice the lab’s gain-of-function researchers would have made? 

Yes, it could have happened randomly, through mutations. But do you believe that? At the minimum, this fact—that the coronavirus, with all its random possibilities, took the rare and unnatural combination used by human researchers—implies that the leading theory for the origin of the coronavirus must be laboratory escape. 

When the lab’s Shi Zhengli and colleagues published a paper in February 2020 with the virus’s partial genome, they omitted any mention of the special sequence that supercharges the virus or the rare double CGG section. Yet the fingerprint is easily identified in the data that accompanied the paper. Was it omitted in the hope that nobody would notice this evidence of the gain-of-function origin? 

But in a matter of weeks virologists Bruno Coutard and colleagues published their discovery of the sequence in CoV-2 and its novel supercharged site. Double CGG is there; you only have to look. They comment in their paper that the protein that held it “may provide a gain-of-function” capability to the virus, “for efficient spreading” to humans.

There is additional scientific evidence that points to CoV-2’s gain-of-function origin. The most compelling is the dramatic differences in the genetic diversity of CoV-2, compared with the coronaviruses responsible for SARS and MERS. 

Both of those were confirmed to have a natural origin; the viruses evolved rapidly as they spread through the human population, until the most contagious forms dominated. Covid-19 didn’t work that way. It appeared in humans already adapted into an extremely contagious version. No serious viral “improvement” took place until a minor variation occurred many months later in England. 

Such early optimization is unprecedented, and it suggests a long period of adaptation that predated its public spread. Science knows of only one way that could be achieved: simulated natural evolution, growing the virus on human cells until the optimum is achieved. That is precisely what is done in gain-of-function research. Mice that are genetically modified to have the same coronavirus receptor as humans, called “humanized mice,” are repeatedly exposed to the virus to encourage adaptation. 

The presence of the double CGG sequence is strong evidence of gene splicing, and the absence of diversity in the public outbreak suggests gain-of-function acceleration. The scientific evidence points to the conclusion that the virus was developed in a laboratory. 

Dr. Quay is founder of Atossa Therapeutics and author of “Stay Safe: A Physician’s Guide to Survive Coronavirus.” Mr. Muller is an emeritus professor of physics at the University of California Berkeley and a former senior scientist at the Lawrence Berkeley National Laboratory.

但凡对美国政治媒体互动关系有所了解的

都会理解这些媒体报道，特别是WSJ系列，

应该是知情人在背后喂料

大家坐稳，大幕刚刚拉开…

Brilliant! Fantastic!

名利场这篇报道，有几家严肃刊物报道了？

fitzroy 发表于 2021-06-06 16:34

抵赖，把头扎进沙子有什么用呢？

https://www.wsj.com/podcasts/opinion-potomac-watch/reading-dr-anthony-fauci-emails/123AE1C3-002F-4658-8DBF-69AC6C8D9A57

17’58”起

https://www.cnn.com/videos/tv/2021/06/05/smerconish-the-coming-crisis-in-confidence.cnn

CBS王牌节目 60 Minutes 跟进

https://www.cbsnews.com/news/covid-19-wuhan-origins-60-minutes-2021-06-06/#app

Gottlieb calls for "broader view" of coronavirus origins， “National Security” perspective

再给你加一个 - msnbc的采访：https://youtu.be/NNm2uMBB-W8

hellensiao 发表于 2021-06-06 21:51

谢谢分享

没有什么比丛原作者口中说的话更保真的了！！！

谢谢hellensiao提供这个链接

这个有一定道理。外国资本打造了完整的产业链和公用设施。不太好全部迁出。

bululu 发表于 2021-06-06 22:23

是会有一个过程

但不能不看到美国已经意识到保证自身产业链安全的重要性

并采取相应行动

重要的是，得道多助，美国不是一个国家在战斗！