"The overall mortality rates in the five-day and 10-day groups were 8.0% (n=16/200) and 10.7% (n=21/197), respectively." 这个?

这是重症的。这个出了数据的是只收重症的。 用20%重症率来算， 那么 [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213]人民的希望[/url]推广后死亡率是20%*8%=1.6%。 这还是假设轻症不用药的情况。


relay 发表于 4/29/2020 10:17:16 AM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83809018#83809018][img][/img][/url]

This is for those hospitalized (住院的, 不一定插管的). I still feel this fatality rate is kind of high for those hospitalized.

你第一句话不对。
一个药若能将病程缩短哪怕25%的时间，对医院对经济对社会的正面影响都会是巨大的。ask any economist, doctor, public health guy

urthur 发表于 4/29/2020 2:16:29 PM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83812077#83812077][img][/img][/url]

我希望看到两组都是15天的结果. 你要知道第一个组吃了药之后11天并不是都好了,11天之后死的就不计在内了

不太明白你的意思。上面有人引用time to recover is 11 days， recover的含义应该包括继续活下去吧


urthur 发表于 4/29/2020 2:22:29 PM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83812177#83812177][img][/img][/url]

No. 用人民希望五天，两周后出院率只有63%。 还比不上用氯喹的。

这要看病人组的重症程度是不是有可比性吧



xiaopangmao 发表于 4/29/2020 2:29:01 PM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83812282#83812282][img][/img][/url]

Two groups were randomly selected. All patients were already sick enough to be hospitalized, but none of them was enough to be put on ventilators before the trial started

Dr. Fauci says the randomized, placebo-controlled study enrolled ~1,090 patients. The primary endpoint was the time to recovery and the ability to be discharged from the hospital. The independent Data Monitoring Committee informed him that remdesivir's clinical benefit was "clear-cut" and highly statistically significant (p<0.001). The drug's mortality benefit, while numerically better, is not yet statistically significant. Remdesivir represents a new standard-of-care for COVID-19. Studies testing remdesivir combined with other meds are next up.