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人民的希望 Remdesivir 4/29新闻

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回复 [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83808337#83808337]1楼Caffeine的帖子[/url] 期待已久的好消息终于来了!!!
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20-04-29 13:04操作
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本来就是应对伊波拉的药,指望它完全对症新冠从来就不现实。短期内没别的药,先拉上顶着而已,好歹比用于应对艾滋病的克利芝感觉离新冠近些


galezhang 发表于 4/29/2020 9:02:58 AM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83808429#83808429][img][/img][/url]

嗯,对SARS也有效果。本质就是就是阻断以RNA作为遗传物质的病毒的自我繁殖,对RNA病毒都有效果,并非是来治愈人体组织,或者杀死活着的病毒。但是能够阻断病毒的自我繁殖,已经对人体很有意义了。可以做一个比喻,人体免疫系统和病毒两军交战,“人民的希望”是来断病毒大军的粮草的。
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20-04-29 13:10操作
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回复 [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&&fid=398&postid=83808438#83808438]6楼victoriabaobei的帖子[/url]
因为我对药和疫苗都很不看好,RNA病毒、ADE效应、大量二次感染和常阳患者的报告,这个冠状病毒哪那么容易被克服。不知道你们这些人的乐观态度都是哪里来的。。。

nyc15 发表于 4/29/2020 9:07:05 AM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83808466#83808466][img][/img][/url]

不光是冠状病毒,任何病毒都不容易克服。人类迄今为止,只有战胜过“天花”病毒,也是因为天花碰巧有个猪队友叫做牛痘。种牛痘也只是让人体免疫系统能够识别天花而已,并非能杀死人体内的天花病毒。严格意义来说,人类抗击病毒唯一的武器只有自身的免疫系统。疫苗和药物都只是辅助作用而已。但是不要小瞧这点辅助作用。
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20-04-29 13:14操作
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划重点: 没有control group。 看得懂英文的好好读读

The main concern, they say, stems from the fact that the Gilead trial expected to read out this week, which was conducted among patients with severe disease, lacks a control group — that is, patients who are randomly assigned to receive the best treatment available, but not remdesivir. As designed, the only randomization is the duration of treatment: either five days or 10 days of drug. Without a true control group of patients, many experts say, it will be difficult to determine whether remdesivir is effective.

“The overall study itself has little or no scientific value since all patients are receiving the drug,” said Steven Nissen, the chief academic officer at the Cleveland Clinic and lead investigator of many trials for heart drugs that have been approved by the Food and Drug Administration.

“The study, as designed, is essentially useless and cannot be used by the FDA for consideration of remdesivir for approval to treat coronavirus,” Nissen said.

Peter Bach, director of the Center for Health Policy and Outcomes at Memorial Sloan Kettering Cancer Center, called the situation “frustrating.”

“For them to run the trial in severe but not include a control group, it’s just such a waste,” Bach said.
cannie 发表于 4/29/2020 9:34:27 AM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83808675#83808675][img][/img][/url]


有对照组的结果还没出来。但是全世界感染病毒的两百多万,重症死亡率一目了然。华尔街不是傻子。
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20-04-29 15:13操作
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内行人一看就知道结论是人造的。生物统计的test 设计是很严格的。哪能这样乱来。

这波炒作,就是华尔街想割韭菜。不信的就进场接盘。


pig0019 发表于 4/29/2020 1:27:49 PM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83811307#83811307][img][/img][/url]

呵呵,看来是金融小白。华尔街如果要割韭菜,就应该卖。华尔街自己砸钱进来,是送韭菜还是割韭菜啊。美股和A股不一样。你以为美股是散户的天下?美股散户全部资金打入市场,也掀不起一滴浪花。美股大盘上下涨幅,基本都是机构一起做起来的(而且不止单个机构)。你顶多可以说机构割机构。华尔街没人有兴趣去割韭菜。韭菜那点钱,还不够一个小机构塞牙缝。。。
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