早就不抱希望了，但是药厂投入巨大，需要拉盘把股票逃出来，弥补损失。小散慎入！



大青椒 发表于 4/29/2020 11:56:40 AM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83810106#83810106][img][/img][/url]

划重点: 没有control group。 看得懂英文的好好读读

The main concern, they say, stems from the fact that the Gilead trial expected to read out this week, which was conducted among patients with severe disease, lacks a control group — that is, patients who are randomly assigned to receive the best treatment available, but not remdesivir. As designed, the only randomization is the duration of treatment: either five days or 10 days of drug. Without a true control group of patients, many experts say, it will be difficult to determine whether remdesivir is effective.

“The overall study itself has little or no scientific value since all patients are receiving the drug,” said Steven Nissen, the chief academic officer at the Cleveland Clinic and lead investigator of many trials for heart drugs that have been approved by the Food and Drug Administration.

“The study, as designed, is essentially useless and cannot be used by the FDA for consideration of remdesivir for approval to treat coronavirus,” Nissen said.

Peter Bach, director of the Center for Health Policy and Outcomes at Memorial Sloan Kettering Cancer Center, called the situation “frustrating.”

“For them to run the trial in severe but not include a control group, it’s just such a waste,” Bach said.
cannie 发表于 4/29/2020 9:34:27 AM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83808675#83808675][img][/img][/url]

建议加上今早Dr. Scott Gottlieb 在CNBC的采访，他说话一直非常谨慎。

As we've been saying for some time now, accumulating data on Remdesivir suggests it's active against covid and there's now enough data to support consideration of access under an emergency use authorization by FDA. The data from NIAID study should push this firmly over the line.

Gilead’s remdesivir, along with therapeutic antibodies and improved testing, is part of “a robust toolbox,” Dr. Scott Gottlieb says. “All of this is going to put us in a much different posture for the fall.” [url=https://t.co/xl18L8D9XO?amp=1]https://cnb.cx/2SgbRfu[/url]

https://twitter.com/ScottGottliebMD/status/1255484418745151495?s=20









fufusix 发表于 4/29/2020 9:19:33 AM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83808565#83808565][img][/img][/url]

Remdesivir的奇妙历程，从西雅图同情用药成功，到公司宣布公开配方允许仿制，国内有人起名人民的希望，到被中国抢注治新冠专利，到国内开始临床实验，到带仿药去意大利，到国内临床试验招不够病人叫停，到不分享临床试验数据，到who泄露部分结果，到唱衰。。。新冠疫情中奇妙的事情也不只这一件，但是作为一个药物，有这样的历程还是蛮玄幻的。
Ruth 发表于 2020-04-29 11:46

觉得中国确实该讨打讨骂。人家为了抗疫，药方都公布了，让你随便用。结果为了自己那点屁利益，连个反馈都不给，好不好使的让人家主人知道一下不行吗？太自私！

他妈的某些中国人心真是坏，黑透了

中国提交的报告，是大大的“NEGATIVE”，结论是，不建议对此药进行其他的实验

炫彩衣飞舞 发表于 4/29/2020 12:27:37 PM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83810450#83810450][img][/img][/url]

Fauci said he was told data from the trial showed a “clear cut positive effect in diminishing time to recover.”
怎么能理解成
FAUCI: DATA SHOWS REMDESIVIR `CLEAR CUT' POSITIVE EFFECT

violabb 发表于 4/29/2020 12:35:14 PM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83810542#83810542][img][/img][/url]

大陆这次整个灾害中一再自我侮辱，世界上还有哪个国家更辱华？大陆帮帮忙，不要一再使我们在中国之外的华人脸上无光。


noshock 发表于 4/29/2020 1:26:40 PM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83811287#83811287][img][/img][/url]

Remdesivir的奇妙历程，从西雅图同情用药成功，到公司宣布公开配方允许仿制，国内有人起名人民的希望，到被中国抢注治新冠专利，到国内开始临床实验，到带仿药去意大利，到国内临床试验招不够病人叫停，到不分享临床试验数据，到who泄露部分结果，到唱衰。。。新冠疫情中奇妙的事情也不只这一件，但是作为一个药物，有这样的历程还是蛮玄幻的。
Ruth 发表于 4/29/2020 11:46:15 AM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83809976#83809976][img][/img][/url]

好消息啊，今天的news都是人民希望有望第一个被批准
express77 发表于 2020-04-29 13:33

赶紧批准吧，这药再没用的话真的是都要绝望了

我昨天在一个群里看见国内有人说，江浙沪其实用了不少此药

express77 发表于 4/29/2020 1:35:41 PM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83811460#83811460][img][/img][/url]

Remdesivir的奇妙历程，从西雅图同情用药成功，到公司宣布公开配方允许仿制，国内有人起名人民的希望，到被中国抢注治新冠专利，到国内开始临床实验，到带仿药去意大利，到国内临床试验招不够病人叫停，到不分享临床试验数据，到who泄露部分结果，到唱衰。。。新冠疫情中奇妙的事情也不只这一件，但是作为一个药物，有这样的历程还是蛮玄幻的。
Ruth 发表于 4/29/2020 11:46:15 AM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83809976#83809976][img][/img][/url]

我昨天在一个群里看见国内有人说，江浙沪其实用了不少此药

express77 发表于 4/29/2020 1:35:41 PM [url=https://forums.huaren.us/showtopic.aspx?topicid=2541213&postid=83811460#83811460][img][/img][/url]

回复47楼 relay 的帖子 你要仔细看报告，进入试验的一个要求是开始给药的时候还没有上呼吸机！所以这根本不是最严重病人的数据，真正严重的病人还没来得及进医院就爆发性呼吸衰竭憋死在家里了。 nyc15 发表于 4/29/2020 10:39:00 AM [url=http://forums.huaren.us/showtopic.aspx?topicid=83809191&postid=83809191#83809191][/url]